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ISO 19290:2021
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS
SKU: iso_081665_177767
Published by ISO
Publication Year 2021
2 Edition
14 pages
Product Details
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).